Therapy For High Risk Prostate Cancer
May 22, 2008
This issue of Prostate Forum represents a shift in Dr. Myers’s
thinking about prostate cancer and was triggered by a series
of key papers in the urology and radiation therapy literature.
We’re sure that this issue will generate considerable controversy.
Dr. Myers thinks that it is now clear that most men diagnosed
with high-risk prostate cancer do not have widespread micrometastases,
but rather are at an increased risk for undetected cancer still
contained within the pelvis.
There are several key questions that need to be answered before
we can treat prostate cancer successfully. Where is the prostate
cancer? How much of it is at each site? What kind of prostate
cancer is it? Can we eliminate the cancer at each site or are
we just going to have to settle for controlling it? While simple
to ask, each of these questions represents an area of active
research and progress in prostate cancer management. At times,
Dr. Myers comes upon papers that shed important new light on
one or more of these questions; he now thinks a study published
in Cancer during the summer of 2007 by Dr. Michael Dattoli is
one of those studies. In this issue of Prostate Forum, Dr. Myers
uses Dattoli’s paper as the jumping off point for a reexamination
of how prostate cancer spreads and what that process implies
for treatment. As a natural progression from Dattoli's paper,
this particular issue will also explore the use of radiation
therapy for high-risk diseases; in subsequent issues, Dr. Myers
will discuss the parallel evolving literature on surgical-based
approaches to high-risk disease.
Read the entire article in Volume 10 Issue 6 of Prostate Forum.
Click here to download this issue now.