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This section contains resources, links, and other items either mentioned in the newsletter or that we think are handy for prostate cancer patients to know.

Partin Coefficient Tables: Prediction of Probability of Organ-Confined Disease
The Partin Tables allow you or you doctor to predict the probability that you have organ-confined prostate cancer on the basis of your Gleason score, your PSA value, and your clinical stage. Be careful to use the table which is based on your PSA value.

Note that the data given in these four tables are roughly the reverse of the data in the tables predicting the probability of a patient having established capsular penetration.

Example
C. is a 59-year-old man with a PSA of 59.3 ng/ml and a Gleason score of 4 + 5 = 9. His doctor has categorized his clinical stage as T2c since he could clearly feel what appeared to be abnormalities in both lobes of C.'s prostate on DRE.

Using the table for PSA values more than 20.0 ng/ml, we find that C. has only a 3% likelihood of organ-confined disease (equivalent to a 97% probability of established capsular penetration). In other words, it is all but certain that the cancer has penetrated into C.'s prostate capsule.
   
 
Prediction of Probability of Organ-Confined Disease
PSA = 0.0-4.0 ng/ml
Gleason Score Stage T1a Stage T1b Stage T1c Stage T2a Stage T2b Stage T2c Stage T3a
2-4 90 80 89 81 72 77 ...
5 82 66 81 68 57 62 40
6 78 61 78 64 52 57 35
7 ... 43 63 47 34 38 19
8-10 ... 31 52 36 24 27 ...
All numbers represent percent predictive probabilities (95% confidence interval); ellipses indicate lack of sufficient data to calculate probability.
 
   
 
Prediction of Probability of Organ-Confined Disease
PSA = 4.1-10.0 ng/ml
Gleason Score Stage T1a Stage T1b Stage T1c Stage T2a Stage T2b Stage T2c Stage T3a
2-4 84 70 83 71 61 66 43
5 72 53 71 55 43 49 27
6 67 47 67 51 38 43 23
7 49 29 49 33 22 25 11
8-10 35 18 37 23 14 15 6
All numbers represent percent predictive probabilities (95% confidence interval); ellipses indicate lack of sufficient data to calculate probability.
 
   
 
Prediction of Probability of Organ-Confined Disease
PSA = 10.1-20.0 ng/ml
Gleason Score Stage T1a Stage T1b Stage T1c Stage T2a Stage T2b Stage T2c Stage T3a
2-4 76 58 75 60 48 53 ...
5 61 40 60 43 32 36 18
6 ... 33 55 38 26 31 14
7 33 17 35 22 13 15 6
8-10 ... 9 23 14 7 8 3
All numbers represent percent predictive probabilities (95% confidence interval); ellipses indicate lack of sufficient data to calculate probability.
 
   
 
Prediction of Probability of Organ-Confined Disease
PSA = 0.0-4.0 ng/ml
Gleason Score Stage T1a Stage T1b Stage T1c Stage T2a Stage T2b Stage T2c Stage T3a
2-4 ... 38 58 41 29 ... ...
5 ... 23 40 26 17 19 8
6 ... 17 35 22 13 15 6
7 ... ... 18 10 5 6 2
8-10 ... 3 10 5 3 3 1
All numbers represent percent predictive probabilities (95% confidence interval); ellipses indicate lack of sufficient data to calculate probability.
 
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