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Partin Coefficient Tables:
Prediction of Probability of Established Capsular Penetration
Last Revised May 14, 1997
Introduction | Example
PSA = 0.0-4.0 ng/ml | PSA
= 4.1-10.0 ng/ml | PSA = 10.1-20.0 ng/ml
| PSA = 20.1 ng/ml or more
Introduction
These four tables give data which allow you or you doctor to predict
the probability that you have established capsular penetration on the
basis of your Gleason score, your PSA value, and your clinical stage. In
other words, these tables allow you to tell whether the prostate cancer
has penetrated into and perhaps through the "walls" or capsule
of the prostate. Be careful to use the table which is based on your PSA
value.
Note that the data given in these four tables are roughly the reverse
of the data in the tables predicting the
probability of a patient having organ-confined disease.
Example
Harry is a 67-year-old man with a PSA of 9.8 ng/ml and a Gleason
score of 2 + 3 = 5. His doctor has categorized his clinical stage as T1c
since his cancer was found solely as a result of an elevated PSA value.
Using the table for PSA values between 4.1 and
10.0 ng/ml, we find that Harry has a 27% likelihood of established
capsular penetration. In other words, there are about 27 chances in 100
that the prostate cancer has penetrated into Harry's prostate capsule.
Prediction of
Established Capsular Penetration
PSA = 0.0-4.0 ng/ml
| Gleason score |
Stage T1a |
Stage T1b |
Stage T1c |
Stage T2a |
Stage T2b |
Stage T2c |
Stage T3a |
| 2-4 |
9 |
19 |
10 |
18 |
25 |
21 |
... |
| 5 |
17 |
32 |
18 |
30 |
40 |
34 |
51 |
| 6 |
19 |
35 |
21 |
34 |
43 |
37 |
53 |
| 7 |
... |
44 |
31 |
45 |
51 |
45 |
52 |
| 8-10 |
... |
43 |
34 |
47 |
48 |
42 |
... |
All numbers represent percent predictive
probabilities (95% confidence interval); ellipses indicate lack
of sufficient data to calculate probability. |
Prediction of
Established Capsular Penetration
PSA = 4.1-10.0 ng/ml
| |
Gleason score |
Stage T1a |
Stage T1b |
Stage T1c |
Stage T2a |
Stage T2b |
Stage T2c |
Stage T3a |
| 2-4 |
14 |
27 |
15 |
26 |
35 |
29 |
44 |
| 5 |
25 |
42 |
27 |
41 |
50 |
43 |
57 |
| 6 |
27 |
44 |
30 |
44 |
52 |
46 |
57 |
| 7 |
36 |
48 |
40 |
52 |
54 |
48 |
48 |
| 8-10 |
34 |
42 |
40 |
49 |
46 |
40 |
34 |
All numbers represent percent predictive
probabilities (95% confidence interval); ellipses indicate lack
of sufficient data to calculate probability. |
|
All numbers represent percent predictive
probabilities (95% confidence interval); ellipses indicate lack
of sufficient data to calculate probability. |
|
All numbers represent percent predictive
probabilities (95% confidence interval); ellipses indicate lack
of sufficient data to calculate probability. |
|
