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The Prostate Forum
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Charles E. Myers, Jr. MD
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Partin Coefficient Tables:
Prediction of Lymph Node Involvement

Last Revised September 25, 1997

Introduction | Example

PSA = 0.0-4.0 ng/ml | PSA = 4.1-10.0 ng/ml | PSA = 10.1-20.0 ng/ml | PSA = 20.1 ng/ml or more

Introduction

The following four tables give data which allow you or you doctor to predict the probability that prostate cancer has spread out of your prostate into the lymph nodes on the basis of your Gleason score, your PSA value, and your clinical stage. Be careful to use the table which is based on your PSA value.

Example

Mike is a 62-year-old man with a PSA of 8.4 ng/ml and a Gleason score of 4 + 2 = 6. His doctor has categorized his clinical stage as T2b since he was able to feel a significant induration in one lobe of Mike's prostate on DRE and the biopsy and ultrasound indicated that the cancer had invaded more than half of that lobe but there was no sign of cancer in the other lobe.

Using the table for PSA values between 4.1 and 10.0 ng/ml, we find that Mike has an 4% likelihood of prostate cancer which has invaded his lymph nodes. In other words, there are about 19 chances in 20 that Mike's cancer has not invaded the lymph nodes.

Prediction of Probability of Lymph Node Involvement
PSA = 0.0-4.0 ng/ml
Gleason score Stage T1a Stage T1b Stage T1c Stage T2a Stage T2b Stage T2c Stage T3a
2-4 0 0 0 0 0 0 ...
5 0 1 0 0 1 1 2
6 1 2 0 1 2 2 5
7 ... 6 1 2 5 5 9
8-10 ... 14 4 5 10 10 ...

All numbers represent percent predictive probabilities (95% confidence interval); ellipses indicate lack of sufficient data to calculate probability.

Prediction of Probability of Lymph Node Involvement
PSA = 4.1-10.0 ng/ml
  Gleason score Stage T1a Stage T1b Stage T1c Stage T2a Stage T2b Stage T2c Stage T3a
2-4 0 1 0 0 1 1 1
5 1 2 0 1 2 2 3
6 3 5 1 2 4 4 9
7 8 12 3 4 9 9 15
8-10 18 23 8 9 16 17 24

All numbers represent percent predictive probabilities (95% confidence interval); ellipses indicate lack of sufficient data to calculate probability.

Prediction of Probability of Lymph Node Involvement
PSA = 10.1-20.0 ng/ml
Gleason score Stage T1a Stage T1b Stage T1c Stage T2a Stage T2b Stage T2c Stage T3a
2-4 0 2 0 1 1 1 ...
5 3 5 1 2 4 4 7
6 ... 13 3 4 10 10 18
7 18 24 8 9 17 18 26
8-10 ... 40 16 17 29 29 37

All numbers represent percent predictive probabilities (95% confidence interval); ellipses indicate lack of sufficient data to calculate probability.

Prediction of Probability of Lymph Node Involvement
PSA = > 20.0 ng/ml
Gleason score Stage T1a Stage T1b Stage T1c Stage T2a Stage T2b Stage T2c Stage T3a
2-4 ... 4 1 1 3 ... ...
5 ... 10 3 3 7 7 11
6 ... 23 7 8 16 17 26
7 ... ... 14 14 25 25 32
8-10 ... 51 24 24 36 35 42

All numbers represent percent predictive probabilities (95% confidence interval); ellipses indicate lack of sufficient data to calculate probability.